PERCEPTIVE ADVISORS LLC

Q3 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
93
Total value ($000)
$3,463,099
Net value change ($000)
+765,741 (28.4%)
New positions
19
Sold out positions
11
Turnover %
9.4%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
CELC 124,239 569.8%
RYTM 93,499 61.2%
Merus N.V. 90,144 242.0%
TVTX 78,344 634.5%
ROIV 73,939 196.9%
AMLX 71,009 140.2%
CNTA 60,126 399.0%
PRAX 51,261 161.9%
ASND 50,038 30.1%
PEN 47,452 563.8%
Top Reduces (Value $000, Stocks/ETFs)
VRNA -464,983 -89.3%
SLNO -36,062 -100.0%
EOLS -22,793 -100.0%
PODD -18,972 -100.0%
BBNX -17,680 -76.2%
CRL -15,173 -100.0%
DYN -14,558 -68.0%
RARE -9,817 -100.0%
IMVT -8,609 -25.2%
VKTX -7,314 -72.5%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 2,010 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type