ARCH Venture Management, LLC

Q3 2025 13F-HR Holdings

Location
Chicago, IL
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
9
Total value ($000)
$492,364
Net value change ($000)
+193,254 (64.6%)
New positions
0
Sold out positions
2
Turnover %
4.7%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
RAPP 68,311 161.0%
MAZE 56,239 111.2%
BEAM 32,961 42.7%
LYEL 28,694 178.1%
GOSS 11,278 113.8%
ERAS 10,005 71.0%
VIR 8,654 13.3%
QTTB 157 32.8%
Top Reduces (Value $000, Stocks/ETFs)
Verve Therapeutics, Inc. -22,559 -100.0%
UNBX -386 -100.0%
CERO -102 -47.2%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type