ARCH Venture Management, LLC

Q2 2026 13F-HR Holdings

Location
Chicago, IL
Holdings as of
6/30/2026
Date filed
8/14/2026
Form type
13F-HR
Num holdings
12
Total value ($000)
$1,100,262
Net value change ($000)
+423,168 (62.5%)
New positions
3
Sold out positions
1
Turnover %
29.2%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PARABILIS MEDICINES INC 175,518 NEW
SEAPORT THERAPEUTICS INC 136,600 NEW
BEAM 47,581 44.0%
RAPP 38,705 33.2%
ERAS 15,176 13.2%
VIR 13,621 11.8%
GENB 8,497 35.0%
BOLD 6,735 NEW
TXG 3,727 80.6%
Top Reduces (Value $000, Stocks/ETFs)
LYEL -19,613 -30.1%
QTTB -2,057 -100.0%
GOSS -1,320 -49.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type