Avoro Capital Advisors LLC

Q4 2021 13F-HR Holdings

Location
New York, NY
Holdings as of
12/31/2021
Date filed
2/14/2022
Form type
13F-HR
Num holdings
41
Total value ($000)
$5,875,773
Net value change ($000)
-490,274 (-7.7%)
New positions
3
Sold out positions
6
Turnover %
19.4%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q3 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
APLS 239,707 145.5%
XBI 117,558 NEW
BMRN 102,461 70.7%
UTHR 102,063 18.4%
XENE 99,959 179.2%
ARGX 52,090 18.2%
SRPT 50,206 21.7%
FOLD 44,838 26.6%
KRYS 33,226 NEW
ALNY 21,810 13.6%
Top Reduces (Value $000, Stocks/ETFs)
XLRN -688,400 -100.0%
Mirati Therapeutics, Inc. -140,098 -15.8%
VRTX -120,443 -100.0%
Trillium Therapeutics Inc. -100,092 -100.0%
ARENA PHARMACEUTICALS INC -89,178 -43.7%
PMVP -53,323 -61.2%
ASND -46,532 -14.7%
IOVA -44,004 -21.0%
Deciphera Pharmaceuticals, Inc. -36,291 -100.0%
BIIB -23,771 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 2,910 (0.0% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type