BAKER BROS. ADVISORS LP

Q2 2022 13F-HR Holdings

Location
New York, NY
Holdings as of
6/30/2022
Date filed
8/15/2022
Form type
13F-HR
Num holdings
117
Total value ($000)
$17,626,987
Net value change ($000)
+223,525 (1.3%)
New positions
5
Sold out positions
6
Turnover %
0.7%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q1 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Seagen Inc. 1,542,944 22.8%
ARGX 71,170 20.2%
BMRN 43,970 7.5%
REPL 35,405 129.4%
ChemoCentryx, Inc. 21,436 93.3%
IMCR 18,678 24.8%
BMEA 18,294 264.4%
ALT 17,753 271.9%
TRDA 15,092 34.2%
NRIX 14,805 43.1%
Top Reduces (Value $000, Stocks/ETFs)
ACAD -424,375 -41.8%
ONC -312,143 -14.2%
INCY -124,698 -4.3%
ASND -81,900 -15.4%
BCRX -72,198 -34.9%
NBIX -63,466 -100.0%
Invitae Corp -54,601 -69.4%
KYMR -44,218 -43.8%
MDGL -39,789 -27.0%
AMARIN CORP PLC -38,106 -54.7%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type