RA CAPITAL MANAGEMENT, L.P.

Q4 2022 13F-HR Holdings

Location
Boston, MA
Holdings as of
12/31/2022
Date filed
2/14/2023
Form type
13F-HR
Num holdings
70
Total value ($000)
$4,930,700
Net value change ($000)
+243,173 (5.2%)
New positions
9
Sold out positions
21
Turnover %
16.3%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q3 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PCVX 170,916 155.5%
DICE Therapeutics, Inc. 108,049 102.3%
VOR 107,019 241.8%
JBIO 105,118 76.7%
VRNA 103,258 167.0%
Inhibrx, Inc. 94,959 NEW
RNAM 85,643 242.0%
89bio, Inc. 68,940 153.0%
ASND 68,218 8.7%
WAVE LIFE SCIENCES LTD 58,315 93.9%
Top Reduces (Value $000, Stocks/ETFs)
Forma Therapeutics Holdings, Inc. -179,782 -100.0%
BIIB -102,757 -41.0%
RLMD -74,040 -100.0%
Third Harmonic Bio, Inc. -63,635 -96.5%
CTKB -60,348 -30.6%
NS Wind Down Co., Inc. -57,627 -98.0%
NKTX -55,963 -54.5%
ENTA -46,513 -100.0%
ABOS -45,239 -46.2%
GERN -39,204 -55.6%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type