BAKER BROS. ADVISORS LP

Q3 2023 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2023
Date filed
11/14/2023
Form type
13F-HR
Num holdings
101
Total value ($000)
$17,351,037
Net value change ($000)
+71,796 (0.4%)
New positions
8
Sold out positions
15
Turnover %
1.4%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Seagen Inc. 877,271 10.2%
RYTM 46,495 43.4%
ROIV 43,685 46.0%
ONC 18,321 0.9%
IMVT 16,316 NEW
RARE 12,594 34.9%
Mirati Therapeutics, Inc. 10,475 20.6%
KNSA 9,243 23.4%
AKRO 9,213 8.3%
ARVN 8,121 NEW
Top Reduces (Value $000, Stocks/ETFs)
INCY -162,048 -7.2%
ACAD -133,308 -13.0%
MDGL -131,273 -36.8%
KOD -88,283 -73.9%
CHINOOK THERAPEUTICS, INC. -55,909 -100.0%
DICE Therapeutics, Inc. -48,123 -100.0%
ARGX -34,844 -31.9%
KYMR -34,558 -34.4%
ImmunoGen, Inc. -28,684 -100.0%
REPL -27,974 -26.3%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type