BAKER BROS. ADVISORS LP

Q1 2024 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2024
Date filed
5/15/2024
Form type
13F-HR
Num holdings
87
Total value ($000)
$7,971,707
Net value change ($000)
-816,894 (-9.3%)
New positions
13
Sold out positions
8
Turnover %
4.5%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q4 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
RVMD 95,649 64.8%
BCYC 90,706 280.2%
KYMR 88,380 57.9%
EWTX 72,469 212.8%
MDGL 70,243 15.4%
KOD 38,429 73.0%
STOK 34,795 325.8%
CELC 25,732 329.8%
DNLI 20,624 36.9%
NRIX 17,003 42.4%
Top Reduces (Value $000, Stocks/ETFs)
ACAD -549,524 -40.9%
ONC -253,336 -13.3%
Mirati Therapeutics, Inc. -242,135 -100.0%
INCY -210,531 -9.3%
IMCR -73,720 -42.8%
Gracell Biotechnologies Inc. -20,883 -100.0%
RYTM -16,892 -5.7%
DAWN -14,600 -100.0%
SPRY -10,995 -100.0%
BCRX -9,215 -15.2%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type