Avoro Capital Advisors LLC

Q3 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
32
Total value ($000)
$7,736,501
Net value change ($000)
+2,026,223 (35.5%)
New positions
3
Sold out positions
3
Turnover %
3.3%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2025 Next filing: 3/13/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MDGL 273,274 48.2%
QURE 208,889 413.4%
ARWR 208,461 124.5%
CNTA 196,396 298.9%
Merus N.V. 167,544 100.9%
UTHR 166,716 24.5%
ASND 156,371 18.2%
GPCR 144,356 NEW
RNAM 132,873 66.4%
KRYS 124,717 34.1%
Top Reduces (Value $000, Stocks/ETFs)
MLTX -181,540 -92.7%
BPMC -48,068 -100.0%
BCRX -30,832 -76.5%
GLUE -16,800 -100.0%
ALKERMES PLC -15,769 -19.0%
RARE -11,999 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 6,678 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type