RA CAPITAL MANAGEMENT, L.P.

Q1 2026 13F-HR Holdings

Location
Boston, MA
Holdings as of
3/31/2026
Date filed
5/15/2026
Form type
13F-HR
Num holdings
85
Total value ($000)
$9,437,744
Net value change ($000)
-323,124 (-3.3%)
New positions
24
Sold out positions
11
Turnover %
26.1%
Sector allocation + QoQ delta (equities-only)
Prev filing: 2/17/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q4 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
SGP 207,827 NEW
PCVX 171,956 34.8%
ASND 159,261 7.3%
DNTH 152,757 230.0%
TYRA 146,505 45.7%
ZLAB 107,354 NEW
SRPT 84,920 NEW
NUVL 70,508 37.3%
EWTX 69,714 26.9%
GLTO 62,142 NEW
Top Reduces (Value $000, Stocks/ETFs)
CDTX -743,410 -100.0%
RNAM -623,278 -100.0%
RYTM -133,803 -18.7%
WAVE LIFE SCIENCES LTD -113,879 -36.8%
PEPG -95,106 -72.8%
ACLX -82,619 -100.0%
BLTE -69,180 -100.0%
MLYS -57,382 -21.6%
IVVD -42,284 -100.0%
SPRY -39,316 -31.1%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type