ORBIMED ADVISORS LLC

Q3 2021 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2021
Date filed
11/15/2021
Form type
13F-HR
Num holdings
172
Total value ($000)
$9,099,330
Net value change ($000)
-787,437 (-8.0%)
New positions
27
Sold out positions
15
Turnover %
11.5%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q2 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
IVVD 227,399 NEW
ZBH 96,715 NEW
HCA 47,039 NEW
ERAS 45,991 NEW
Seagen Inc. 45,506 NEW
BIIB 42,937 184.0%
CTKB 41,174 NEW
Mirati Therapeutics, Inc. 38,727 19.0%
HELP 29,463 NEW
PRLD 26,304 9.2%
Top Reduces (Value $000, Stocks/ETFs)
SPRY -182,772 -67.7%
SpringWorks Therapeutics, Inc. -115,672 -23.2%
AUPH -78,655 -100.0%
Acutus Medical, Inc. -69,604 -74.8%
EWTX -65,958 -22.2%
ASND -58,916 -100.0%
NTRA -58,349 -25.0%
VRTX -55,665 -25.9%
ABCL -53,123 -38.8%
ELV -50,963 -39.8%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 9,898 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type