ORBIMED ADVISORS LLC

Q1 2022 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2022
Date filed
5/16/2022
Form type
13F-HR
Num holdings
145
Total value ($000)
$6,167,262
Net value change ($000)
-1,611,193 (-20.7%)
New positions
9
Sold out positions
28
Turnover %
14.7%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Biohaven Pharmaceutical Holding Co Ltd. 85,256 NEW
Global Blood Therapeutics, Inc. 54,613 NEW
ARGX 53,540 NEW
BMRN 50,927 67.0%
PFE 47,749 30.9%
Sierra Oncology, Inc. 30,854 96.1%
THC 29,584 121.1%
ISRG 26,851 20.0%
SIBN 19,746 38.6%
EVH 19,266 74.2%
Top Reduces (Value $000, Stocks/ETFs)
MRK -136,366 -100.0%
XBI -102,997 -91.1%
HCA -100,070 -100.0%
BMY -80,147 -29.6%
EWTX -77,812 -36.5%
Mirati Therapeutics, Inc. -75,179 -35.9%
SVA -72,700 -100.0%
ZBH -71,689 -100.0%
NTRA -67,152 -50.9%
PRLD -55,720 -44.6%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 7,834 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 ORBIMED CAPITAL LLC 028-10410