ORBIMED ADVISORS LLC

Q3 2023 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2023
Date filed
11/14/2023
Form type
13F-HR
Num holdings
127
Total value ($000)
$4,707,565
Net value change ($000)
-811,345 (-14.7%)
New positions
16
Sold out positions
14
Turnover %
16.5%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q2 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MRK 108,612 NEW
APLM 63,590 1675.2%
RayzeBio, Inc. 58,229 NEW
Mirati Therapeutics, Inc. 52,326 158.5%
ABBV 49,190 NEW
ICLR 32,554 NEW
APGE 30,414 NEW
NMRA 21,165 NEW
CI 21,048 46.6%
NPCE 21,024 116.7%
Top Reduces (Value $000, Stocks/ETFs)
Theseus Pharmaceuticals, Inc. -113,140 -70.4%
BMY -95,158 -100.0%
VectivBio Holding AG -87,662 -100.0%
UNH -81,983 -69.9%
BAX -69,231 -45.0%
ISRG -66,321 -31.3%
ELVN -60,739 -33.1%
ACELYRIN, Inc. -57,152 -51.3%
EW -48,580 -100.0%
MDGL -37,289 -50.2%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 45,975 (1.0% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type