ADAGE CAPITAL PARTNERS GP, L.L.C.

Q4 2025 13F-HR Holdings

Location
Boston, MA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
905
Total value ($000)
$66,075,304
Net value change ($000)
+2,937,033 (4.7%)
New positions
165
Sold out positions
149
Turnover %
7.7%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
GOOGL 358,513 27.9%
LLY 278,809 45.3%
GOOGL 258,902 24.6%
TERN 194,638 658.0%
MRK 194,491 219.9%
AAPL 192,220 5.6%
BA 159,473 91.8%
PRAX 158,689 126.1%
RVMD 141,002 406.7%
RNAM 137,488 263.0%
Top Reduces (Value $000, Stocks/ETFs)
MSFT -306,860 -8.7%
CVX -238,788 -46.8%
PG -177,124 -30.5%
META -135,039 -9.2%
89bio, Inc. -133,735 -100.0%
INSM -128,161 -71.1%
HD -105,011 -22.3%
ABT -97,020 -31.5%
SLNO -94,747 -100.0%
JCI -94,419 -33.6%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 10,288 (0.0% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type