MPM BioImpact LLC

Q4 2025 13F-HR Holdings

Location
Boston, MA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
38
Total value ($000)
$873,953
Net value change ($000)
+263,074 (43.1%)
New positions
15
Sold out positions
17
Turnover %
51.4%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
LQDA 43,768 962.4%
AGIO 35,478 NEW
CGEM 33,806 74.5%
QURE 33,062 NEW
RVMD 25,533 173.2%
ALMS 23,443 NEW
CRVS 21,126 NEW
URGN 19,354 718.7%
GLUE 18,399 NEW
DRUG 17,961 NEW
Top Reduces (Value $000, Stocks/ETFs)
RNAM -33,114 -100.0%
ZLAB -25,250 -100.0%
CMPX -17,766 -100.0%
ALKERMES PLC -16,478 -100.0%
VERA -16,363 -100.0%
JANX -15,013 -100.0%
SPRY -13,099 -100.0%
SRPT -11,983 -88.8%
RARE -11,903 -100.0%
WAVE LIFE SCIENCES LTD -11,019 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type