SR ONE CAPITAL MANAGEMENT, LP

Q1 2026 13F-HR Holdings

Location
Redwood City, CA
Holdings as of
3/31/2026
Date filed
5/14/2026
Form type
13F-HR
Num holdings
14
Total value ($000)
$915,442
Net value change ($000)
+209,065 (29.6%)
New positions
1
Sold out positions
0
Turnover %
16.6%
Sector allocation + QoQ delta (equities-only)
Prev filing: 2/12/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q4 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MANE 151,678 NEW
ACLX 116,440 76.1%
ALMS 24,048 125.7%
ORIC 20,723 54.9%
DSGN 8,224 13.4%
ORKA 8,065 61.8%
OCS 4,244 33.2%
NKTX 866 14.0%
Top Reduces (Value $000, Stocks/ETFs)
ZBIO -84,434 -46.2%
SPRY -14,526 -31.1%
MLYS -14,388 -25.4%
CRSP -9,929 -9.3%
ENGN -1,660 -24.6%
RARE -282 -8.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type