DEERFIELD MANAGEMENT COMPANY, L.P.

Q4 2025 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
150
Total value ($000)
$7,830,166
Net value change ($000)
+1,279,426 (19.5%)
New positions
31
Sold out positions
34
Turnover %
14.7%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PRAX 221,689 497.5%
COGT 191,236 147.1%
NUVL 179,158 11.5%
CELC 134,718 371.8%
VERA 99,771 94.3%
ARWR 87,440 255.3%
INSP 61,148 78.7%
RVMD 60,085 35.2%
STOK 57,878 NEW
LNTH 55,103 NEW
Top Reduces (Value $000, Stocks/ETFs)
Merus N.V. -286,867 -100.0%
BMY -105,433 -100.0%
MRK -86,448 -100.0%
PFE -84,181 -100.0%
INSM -67,829 -100.0%
CNC -57,426 -17.8%
INDV -46,709 -27.7%
ZBIO -34,697 -100.0%
NEO -34,333 -100.0%
CNMD -33,618 -94.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 29,490 (0.4% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 Deerfield UGP, LLC 028-25875