DAFNA Capital Management LLC

Q4 2025 13F-HR Holdings

Location
Los Angeles, CA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
77
Total value ($000)
$430,519
Net value change ($000)
+25,733 (6.4%)
New positions
12
Sold out positions
10
Turnover %
12.5%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 11/14/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
RVMD 17,460 56.9%
BHVN 7,254 205.4%
PRCT 3,775 NEW
MBX 3,724 250.3%
HELP 3,722 NEW
TNDM 3,495 81.1%
IDYA 2,827 19.2%
DNLI 2,811 114.9%
ATRC 2,756 13.2%
MPLT 2,525 NEW
Top Reduces (Value $000, Stocks/ETFs)
Merus N.V. -20,755 -100.0%
STXS -11,082 -26.0%
SLNO -3,583 -100.0%
CMPX -3,313 -100.0%
IBB -3,306 -22.3%
KRRO -2,912 -100.0%
SNDX -1,865 -24.2%
MLYS -1,769 -55.9%
KURA -1,650 -40.2%
KROS -1,277 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type