Darwin Global Management, Ltd.

Q4 2021 13F-HR Holdings

Location
St. Helier, Y9
Holdings as of
12/31/2021
Date filed
2/14/2022
Form type
13F-HR
Num holdings
13
Total value ($000)
$654,588
Net value change ($000)
+111,308 (20.5%)
New positions
5
Sold out positions
4
Turnover %
132.8%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/15/2021 Next filing: 5/16/2022 SEC filing

Snapshot: Change Analysis

Compared to Q3 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PFE 454,553 NEW
AZN 29,819 NEW
ENTA 12,428 NEW
Inhibrx, Inc. 7,778 43.0%
KROS 6,524 NEW
ChemoCentryx, Inc. 5,891 NEW
FULC 4,656 485.5%
VIR 4,134 209.6%
ACRS 274 9.6%
Top Reduces (Value $000, Stocks/ETFs)
XLRN -344,200 -100.0%
NTLA -29,279 -29.0%
BNTX -13,072 -36.0%
FATE -11,954 -57.1%
BBIO -11,891 -100.0%
IVVD -3,655 -100.0%
Verve Therapeutics, Inc. -436 -33.9%
JBIO -262 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type