Frazier Life Sciences Management, L.P.

Q3 2022 13F-HR Holdings

Location
Menlo Park, CA
Holdings as of
9/30/2022
Date filed
11/14/2022
Form type
13F-HR
Num holdings
43
Total value ($000)
$1,298,702
Net value change ($000)
+239,062 (22.6%)
New positions
7
Sold out positions
5
Turnover %
14.2%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
HilleVax, Inc. 65,277 64.3%
RYTM 46,403 NEW
PHAT 43,968 89.4%
Allakos Inc. 29,327 NEW
VRNA 21,457 NEW
CHINOOK THERAPEUTICS, INC. 20,984 33.4%
SNDX 20,530 33.4%
ACAD 14,026 NEW
COGT 12,057 63.8%
MIRM 11,010 15.9%
Top Reduces (Value $000, Stocks/ETFs)
Sierra Oncology, Inc. -47,876 -100.0%
ARQT -13,777 -7.7%
VRDN -11,342 -100.0%
Gracell Biotechnologies Inc. -7,808 -45.6%
PASG -7,126 -60.3%
ALPINE IMMUNE SCIENCES, INC. -3,912 -15.4%
AUTL -2,586 -24.4%
PCVX -1,756 -4.5%
SLN -1,745 -16.7%
IVERIC bio, Inc. -1,635 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type