Exome Asset Management LLC

Q4 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
12/31/2025
Date filed
2/13/2026
Form type
13F-HR
Num holdings
60
Total value ($000)
$209,146
Net value change ($000)
+44,001 (26.6%)
New positions
20
Sold out positions
19
Turnover %
46.2%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PRAX 11,725 216.9%
WAVE LIFE SCIENCES LTD 7,165 NEW
ELV 6,026 NEW
JAZZ 4,504 NEW
COGT 4,485 70.4%
GH 3,894 63.5%
AGIO 3,728 NEW
ELVN 3,424 NEW
CELC 3,420 NEW
APLS 3,413 NEW
Top Reduces (Value $000, Stocks/ETFs)
89bio, Inc. -4,023 -100.0%
APGE -3,751 -100.0%
NBP -3,454 -63.5%
CVS -3,287 -100.0%
SLNO -3,275 -100.0%
AKRO -2,781 -100.0%
GERN -2,546 -100.0%
THC -2,466 -67.1%
CNTA -2,135 -100.0%
COR -1,875 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 6,718 (3.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type