Caligan Partners LP

Q4 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
24
Total value ($000)
$1,214,793
Net value change ($000)
+451,284 (59.1%)
New positions
8
Sold out positions
4
Turnover %
24.8%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
LQDA 95,397 51.7%
PCVX 78,660 NEW
ABVX 72,531 58.8%
RVMD 52,563 105.8%
TNGX 33,047 NEW
MAZE 22,794 NEW
RAPT 21,826 NEW
INBX 17,601 221.1%
ADMA 16,295 42.2%
TYRA 15,076 154.6%
Top Reduces (Value $000, Stocks/ETFs)
AGIO -45,407 -100.0%
EOLS -25,413 -100.0%
Merus N.V. -20,426 -100.0%
MLYS -4,519 -4.3%
AURA -1,404 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 122,347 (10.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type