PFM Health Sciences, LP

Q4 2025 13F-HR Holdings

Location
San Francisco, CA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
78
Total value ($000)
$1,003,020
Net value change ($000)
-297,492 (-22.9%)
New positions
30
Sold out positions
20
Turnover %
45.8%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
GKOS 22,771 NEW
TMO 20,848 1858.1%
MDT 20,537 NEW
SYK 17,873 NEW
UNH 16,683 NEW
NBIX 15,110 188.0%
DXCM 15,090 NEW
AMRX 14,903 418.4%
INBX 12,905 159.9%
CAH 12,811 NEW
Top Reduces (Value $000, Stocks/ETFs)
LLY -98,392 -57.3%
MCK -55,865 -100.0%
ISRG -25,889 -74.8%
COR -25,156 -100.0%
OM -22,457 -91.9%
HCA -21,559 -76.9%
ELV -19,638 -100.0%
NTRA -18,607 -100.0%
AXSM -18,464 -28.7%
CVS -17,584 -67.3%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 15,320 (1.5% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type