RTW INVESTMENTS, LP
Q4 2022 13F-HR Holdings
Net value change ($000)
+561,067
(12.9%)
New positions
1
Sold out positions
9
Turnover %
1.5%
Sector allocation + QoQ delta (equities-only)
Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown
Snapshot: Change Analysis
Compared to Q3 2022
Methodology:
sector metrics are equities-only;
instrument mix chart is ex-options;
options exposure is shown separately.
Why this matters.
Top Adds (Value $000, Stocks/ETFs)
| Prometheus Biosciences, Inc. | 180,754 | 96.0% |
| AXSM | 145,903 | 173.7% |
| IMCR | 108,318 | 51.8% |
| RCKT | 93,937 | 37.2% |
| RARE | 86,060 | 88.1% |
| ALNY | 63,109 | 18.7% |
| CLDX | 50,766 | 58.6% |
| RNAM | 39,949 | 47.3% |
| Mirati Therapeutics, Inc. | 33,584 | 25.5% |
| ESTA | 26,483 | 20.5% |
Top Reduces (Value $000, Stocks/ETFs)
| RLMD | -90,681 | -92.6% |
| PTCT | -67,814 | -24.0% |
| IVERIC bio, Inc. | -47,449 | -73.0% |
| CinCor Pharma, Inc. | -28,531 | -62.6% |
| GH | -27,354 | -70.0% |
| MIST | -22,568 | -56.9% |
| ACET | -22,395 | -37.1% |
| 2seventy bio, Inc. | -17,889 | -100.0% |
| TNDM | -15,408 | -100.0% |
| PMVP | -13,942 | -26.9% |
Instrument mix + QoQ Δ (ex-options)
How this table is calculated:
SEC
VALUE ($000) is used as reported.
For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received.
Column % is bucket-based:
non-options share is calculated inside non-option total, options share is calculated inside options total.
Details.
Filter:
Instrument:
| Issuer Name | Ticker | Sector | Industry | Class | History | Value ($000) | % | Shares | Shares Δ | Shares Δ% | Value Δ ($000) | Value Δ% | Principal | Option Type |
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