Samsara BioCapital, LLC

Q3 2025 13F-HR Holdings

Location
Palo Alto, CA
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
27
Total value ($000)
$765,929
Net value change ($000)
+276,984 (56.6%)
New positions
2
Sold out positions
4
Turnover %
5.3%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MLYS 160,717 209.3%
KLRS 35,604 116.5%
SEPN 25,949 78.0%
AQST 13,975 NEW
SRRK 10,215 5.1%
GOSS 8,583 113.8%
ABVX 6,405 NEW
LENZ 5,923 58.9%
VTVT 5,642 181.9%
PVLA 5,484 71.6%
Top Reduces (Value $000, Stocks/ETFs)
CRGX -18,193 -100.0%
AURA -2,646 -42.3%
TNGX -1,075 -100.0%
HilleVax, Inc. -795 -100.0%
JBIO -722 -13.6%
ARTV -440 -100.0%
ZYME -343 -8.8%
RYTM -132 -4.1%
BOLT -43 -14.2%
ACLX -17 -0.3%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type