Patient Square Capital LP

Q4 2025 13F-HR Holdings

Location
Menlo Park, CA
Holdings as of
12/31/2025
Date filed
2/12/2026
Form type
13F-HR
Num holdings
28
Total value ($000)
$467,132
Net value change ($000)
+93,275 (24.9%)
New positions
9
Sold out positions
5
Turnover %
21.5%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/10/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ONC 21,058 NEW
MIRM 15,950 208.7%
TERN 12,928 NEW
COGT 11,273 NEW
ARGX 10,433 91.3%
CELC 7,029 142.3%
DBVT 6,883 NEW
PHVS 6,443 74.8%
XENE 6,118 NEW
ARQT 6,098 NEW
Top Reduces (Value $000, Stocks/ETFs)
ROIV -11,619 -6.2%
CDTX -11,587 -100.0%
AGIO -5,372 -100.0%
QURE -4,378 -100.0%
NRIX -4,040 -100.0%
OCUL -2,409 -28.8%
LQDA -1,267 -13.9%
GERN -1,158 -100.0%
INSM -536 -1.1%
ELVN -390 -7.6%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type