Paradigm Biocapital Advisors LP

Q1 2023 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2023
Date filed
5/15/2023
Form type
13F-HR
Num holdings
25
Total value ($000)
$1,055,175
Net value change ($000)
+203,273 (23.9%)
New positions
7
Sold out positions
5
Turnover %
29.9%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q4 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
KROS 39,743 NEW
ONC 39,660 NEW
Cerevel Therapeutics Holdings, Inc. 38,907 NEW
ARGX 33,575 99.0%
BIIB 31,076 47.0%
ACLX 26,830 98.2%
XENE 23,302 NEW
INCY 22,685 33.1%
Seagen Inc. 20,299 55.2%
LEGN 20,169 38.3%
Top Reduces (Value $000, Stocks/ETFs)
Horizon Therapeutics Public Ltd Co -54,349 -100.0%
AKRO -33,129 -100.0%
Karuna Therapeutics, Inc. -20,870 -100.0%
ARVN -20,512 -100.0%
Poseida Therapeutics, Inc. -9,602 -74.4%
VOR -7,993 -18.7%
Mirati Therapeutics, Inc. -5,520 -9.6%
ASND -5,468 -12.7%
PRTA -4,519 -100.0%
SNDX -1,704 -3.4%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type