Paradigm Biocapital Advisors LP

Q3 2023 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2023
Date filed
11/14/2023
Form type
13F-HR
Num holdings
31
Total value ($000)
$1,473,653
Net value change ($000)
+179,482 (13.9%)
New positions
6
Sold out positions
6
Turnover %
21.2%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ARGX 73,090 131.8%
OLMA 62,683 186.1%
IRON 59,772 NEW
CRNX 39,658 157.8%
ACLX 31,746 42.8%
TGTX 30,255 NEW
NUVL 28,056 59.4%
BCYC 22,506 44.4%
Mirati Therapeutics, Inc. 20,500 39.3%
UTHR 16,789 31.9%
Top Reduces (Value $000, Stocks/ETFs)
Karuna Therapeutics, Inc. -61,500 -100.0%
ONC -38,529 -100.0%
INCY -33,297 -38.7%
VIR -24,879 -100.0%
MDGL -19,635 -100.0%
MLTX -18,850 -100.0%
Theseus Pharmaceuticals, Inc. -18,197 -100.0%
SNDX -16,033 -31.6%
VOR -6,268 -31.4%
IMCR -4,292 -5.6%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 7,491 (0.5% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type