Darwin Global Management, Ltd.

Q4 2022 13F-HR Holdings

Location
St. Helier, Y9
Holdings as of
12/31/2022
Date filed
2/14/2023
Form type
13F-HR
Num holdings
4
Total value ($000)
$160,625
Net value change ($000)
+94,220 (141.9%)
New positions
4
Sold out positions
2
Turnover %
141.3%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2022 Next filing: 5/15/2023 SEC filing

Snapshot: Change Analysis

Compared to Q3 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ARGX 112,778 NEW
KROS 20,578 NEW
Ambrx Biopharma Cayman, Inc. 17,217 NEW
Prometheus Biosciences, Inc. 10,052 NEW
Top Reduces (Value $000, Stocks/ETFs)
VTYX -48,913 -100.0%
Karuna Therapeutics, Inc. -17,492 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type