Darwin Global Management, Ltd.

Q4 2024 13F-HR Holdings

Location
St. Helier, Y9
Holdings as of
12/31/2024
Date filed
2/14/2025
Form type
13F-HR
Num holdings
6
Total value ($000)
$1,055,769
Net value change ($000)
-174,017 (-14.2%)
New positions
3
Sold out positions
2
Turnover %
35.6%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2024 Next filing: 5/15/2025 SEC filing

Snapshot: Change Analysis

Compared to Q3 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
INSM 128,495 16.8%
JAZZ 59,668 NEW
VRNA 37,637 NEW
NRIX 3,084 NEW
Top Reduces (Value $000, Stocks/ETFs)
PCVX -251,187 -100.0%
GERN -66,179 -66.1%
KROS -61,776 -69.8%
SMMT -23,759 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type