Boxer Capital Management, LLC

Q4 2025 13F-HR Holdings

Location
San Diego, CA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
45
Total value ($000)
$456,876
Net value change ($000)
+143,149 (45.6%)
New positions
15
Sold out positions
4
Turnover %
26.6%
Sector allocation + QoQ delta (equities-only)
Prev filing: 2/17/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
KOD 19,485 158.7%
CELC 17,996 404.8%
TERN 15,150 NEW
TNGX 14,283 17.4%
PRAX 13,693 NEW
RVMD 13,180 70.6%
PALI 11,280 NEW
SRZN 9,405 NEW
CAPR 9,380 NEW
COGT 7,992 NEW
Top Reduces (Value $000, Stocks/ETFs)
QURE -39,756 -85.1%
Merus N.V. -11,298 -100.0%
NKTR -7,113 -100.0%
CYTK -4,638 -42.2%
DNLI -3,630 -100.0%
AMLX -2,567 -21.0%
SLDB -2,010 -54.3%
SRPT -1,590 -33.0%
INO -1,171 -21.8%
TIL -1,084 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type