Ionis Pharmaceuticals Inc

MANUFACTURERS LIFE INSURANCE COMPANY, THE IONS

Report date

12/31/2025

Quarter

2025 Q4

Filed

2/13/2026

Shares

153,241

Value ($000)

12,105

Weight

0.0%

2019 Q4 - 2025 Q4 (16 filings)

Shares History

History scope: non-option holdings only (PUT/CALL rows excluded).

All 13F Holders	Filing date	Value ($000s)	% of Holdings	Shares	Reporting period
2025 Q4	2/13/2026	12,105	0.0%	153,241	12/31/2025
2025 Q2	8/14/2025	3,295	0.0%	83,386	6/30/2025
2025 Q1	5/15/2025	2,517	0.0%	83,440	3/31/2025
2024 Q4	2/14/2025	10,008	0.0%	286,279	12/31/2024
2024 Q3	11/13/2024	12,376	0.0%	308,947	9/30/2024
2024 Q2	8/14/2024	13,099	0.0%	274,850	6/30/2024
2024 Q1	5/14/2024	10,624	0.0%	245,067	3/31/2024
2023 Q4	2/13/2024	13,189	0.0%	260,702	12/31/2023
2023 Q3	11/15/2023	10,418	0.0%	229,677	9/30/2023
2023 Q2	8/11/2023	10,814	0.0%	263,559	6/30/2023
2023 Q1	5/15/2023	2,595	0.0%	72,612	3/31/2023
2022 Q4	8/11/2023	3,084	0.0%	82,523	12/31/2022
2022 Q3	8/11/2023	3,945	0.0%	89,096	9/30/2022
2022 Q2	8/11/2023	3,499	0.0%	93,214	6/30/2022
2022 Q1	8/11/2023	2,692	0.0%	75,298	3/31/2022
2019 Q4	2/14/2020	214	0.0%	3,543	12/31/2019