ACELYRIN, Inc. - 00445A100
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | History | Reduced | 5,805,096 | 14,338 | 0.0% | 0.0% | 1 | -215,772 | -3.58% | Q1 2025 | May 02, 2025 |
| VANGUARD GROUP INC | History | Reduced | 4,079,706 | 10,076 | 0.0% | 0.0% | 2 | -304 | -0.01% | Q1 2025 | May 09, 2025 |
| ORBIMED ADVISORS LLC | History | No change | 4,001,711 | 9,884 | 0.24% | 0.26% | 3 | 0 | 0.0% | Q1 2025 | May 15, 2025 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Added to | 1,773,818 | 4,382 | 0.0% | 0.0% | 4 | +64,732 | 3.79% | Q1 2025 | May 13, 2025 |
| STATE STREET CORP | History | Reduced | 1,420,068 | 3,507 | 0.0% | 0.0% | 5 | -21,205 | -1.47% | Q1 2025 | May 15, 2025 |
| BALYASNY ASSET MANAGEMENT L.P. | History | New | 1,305,015 | 3,223 | 0.01% | — | 6 | +1,305,015 | New | Q1 2025 | May 15, 2025 |
| Alyeska Investment Group, L.P. | History | Reduced | 615,878 | 1,521 | 0.01% | 0.02% | 7 | -900,000 | -59.37% | Q1 2025 | May 15, 2025 |
| RENAISSANCE TECHNOLOGIES LLC | History | Added to | 599,800 | 1,481 | 0.0% | 0.0% | 8 | +132,879 | 28.46% | Q1 2025 | May 14, 2025 |
| NORTHERN TRUST CORP | History | Reduced | 598,151 | 1,477 | 0.0% | 0.0% | 9 | -31,900 | -5.06% | Q1 2025 | May 13, 2025 |
| JPMORGAN CHASE & CO | History | Reduced | 590,846 | 1,459 | 0.0% | 0.0% | 10 | -27,281 | -4.41% | Q1 2025 | May 12, 2025 |
| CANTOR FITZGERALD, L. P. | History | New | 588,664 | 1,454 | 0.03% | — | 11 | +588,664 | New | Q1 2025 | May 15, 2025 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | Reduced | 544,575 | 1,345 | 0.0% | 0.0% | 12 | -69,899 | -11.38% | Q1 2025 | Sep 15, 2025 |
| GOLDMAN SACHS GROUP INC | History | Reduced | 351,407 | 867 | 0.0% | 0.0% | 13 | -218,503 | -38.34% | Q1 2025 | Jun 27, 2025 |
| MORGAN STANLEY | History | Reduced | 275,815 | 681 | 0.0% | 0.0% | 14 | -2,047,706 | -88.13% | Q1 2025 | May 15, 2025 |
| Nuveen, LLC | History | New | 202,239 | 499 | 0.0% | — | 15 | +202,239 | New | Q1 2025 | May 12, 2025 |
| AQR CAPITAL MANAGEMENT LLC | History | New | 193,323 | 477 | 0.0% | — | 16 | +193,323 | New | Q1 2025 | May 15, 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | History | Reduced | 179,150 | 442 | 0.0% | 0.46% | 17 | -1,389 | -0.77% | Q1 2025 | May 13, 2025 |
| CITADEL ADVISORS LLC | History | Reduced | 178,037 | 439 | 0.0% | 0.0% | 18 | -4,041,879 | -95.78% | Q1 2025 | May 15, 2025 |
| Bank of New York Mellon Corp | History | Reduced | 173,277 | 427 | 0.0% | 0.0% | 19 | -3,622 | -2.05% | Q1 2025 | Apr 29, 2025 |
| MILLENNIUM MANAGEMENT LLC | History | Reduced | 149,298 | 368 | 0.0% | 0.01% | 20 | -4,565,104 | -96.83% | Q1 2025 | May 15, 2025 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | History | New | 140,900 | 348 | 0.01% | — | 21 | +140,900 | New | Q1 2025 | May 15, 2025 |
| BLAIR WILLIAM & CO/IL | History | No change | 138,595 | 342 | 0.0% | 0.0% | 22 | 0 | 0.0% | Q1 2025 | May 09, 2025 |
| FRANKLIN RESOURCES INC | History | Added to | 127,023 | 313 | 0.0% | 0.0% | 23 | +36,469 | 40.27% | Q1 2025 | May 13, 2025 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | Added to | 121,369 | 299 | 0.0% | 0.0% | 24 | +86,545 | 248.52% | Q1 2025 | May 14, 2025 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | History | Reduced | 109,612 | 270 | 0.0% | 0.0% | 25 | -12,391 | -10.16% | Q1 2025 | May 05, 2025 |
| UBS Group AG | History | Reduced | 103,525 | 255 | 0.0% | 0.0% | 26 | -83,480 | -44.64% | Q1 2025 | May 13, 2025 |
| XTX Topco Ltd | History | Added to | 103,047 | 254 | 0.01% | 0.0% | 27 | +92,678 | 893.8% | Q1 2025 | May 08, 2025 |
| RHUMBLINE ADVISERS | History | Reduced | 102,174 | 252 | 0.0% | 0.0% | 28 | -6,069 | -5.61% | Q1 2025 | May 29, 2025 |
| AMERICAN CENTURY COMPANIES INC | History | Added to | 91,390 | 225 | 0.0% | 0.0% | 29 | +12,522 | 15.88% | Q1 2025 | May 13, 2025 |
| Invesco Ltd. | History | Added to | 85,520 | 211 | 0.0% | 0.0% | 30 | +59,754 | 231.91% | Q1 2025 | May 12, 2025 |
| BARCLAYS PLC | History | Reduced | 82,871 | 204 | 0.0% | 0.0% | 31 | -33,773 | -28.95% | Q1 2025 | Mar 17, 2026 |
| ALPS ADVISORS INC | History | Reduced | 74,640 | 184 | 0.0% | 0.0% | 32 | -6,489 | -8.0% | Q1 2025 | Apr 30, 2025 |
| ALLIANCEBERNSTEIN L.P. | History | No change | 73,670 | 181 | 0.0% | 0.0% | 33 | 0 | 0.0% | Q1 2025 | May 15, 2025 |
| DEUTSCHE BANK AG\ | History | Reduced | 61,539 | 152 | 0.0% | 0.0% | 34 | -8,461 | -12.09% | Q1 2025 | May 09, 2025 |
| CITIGROUP INC | History | Reduced | 53,629 | 132 | 0.0% | 0.0% | 35 | -4,282 | -7.39% | Q1 2025 | May 12, 2025 |
| MARSHALL WACE, LLP | History | Reduced | 53,100 | 131 | 0.0% | 0.0% | 36 | -518,948 | -90.72% | Q1 2025 | May 15, 2025 |
| WELLS FARGO & COMPANY/MN | History | Added to | 52,608 | 129 | 0.0% | 0.0% | 37 | +594 | 1.14% | Q1 2025 | May 13, 2025 |
| LMR Partners LLP | History | New | 50,000 | 123 | 0.0% | — | 39 | +50,000 | New | Q1 2025 | May 15, 2025 |
| INTECH INVESTMENT MANAGEMENT LLC | History | Added to | 49,830 | 123 | 0.0% | 0.0% | 38 | +23,243 | 87.42% | Q1 2025 | May 20, 2025 |
| DIMENSIONAL FUND ADVISORS LP | History | Reduced | 44,755 | 110 | 0.0% | 0.0% | 40 | -73,486 | -62.15% | Q1 2025 | May 13, 2025 |
| STRS OHIO | History | No change | 44,300 | 109 | 0.0% | 0.0% | 41 | 0 | 0.0% | Q1 2025 | May 28, 2025 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | History | Added to | 43,780 | 108 | 0.0% | 0.0% | 42 | +1,872 | 4.47% | Q1 2025 | May 15, 2025 |
| BANK OF AMERICA CORP /DE/ | History | Reduced | 36,410 | 89 | 0.0% | 0.0% | 43 | -161,425 | -81.6% | Q1 2025 | May 15, 2025 |
| Mariner, LLC | History | New | 31,389 | 77 | 0.0% | — | 44 | +31,389 | New | Q1 2025 | May 15, 2025 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | History | Added to | 28,717 | 70 | 0.0% | 0.0% | 45 | +613 | 2.18% | Q1 2025 | May 15, 2025 |
| VOYA INVESTMENT MANAGEMENT LLC | History | Reduced | 20,768 | 51 | 0.0% | 0.0% | 46 | -1,514 | -6.79% | Q1 2025 | Jun 18, 2025 |
| MetLife Investment Management, LLC | History | Reduced | 18,493 | 45 | 0.0% | 0.0% | 47 | -24,359 | -56.84% | Q1 2025 | May 14, 2025 |
| NISA INVESTMENT ADVISORS, LLC | History | Added to | 16,586 | 40 | 0.0% | — | 48 | +16,503 | 19883.13% | Q1 2025 | Apr 30, 2025 |
| CIBC WORLD MARKETS CORP | History | New | 16,427 | 40 | 0.0% | — | 49 | +16,427 | New | Q1 2025 | May 13, 2025 |
| NEW YORK STATE COMMON RETIREMENT FUND | History | No change | 15,512 | 38 | 0.0% | 0.0% | 50 | 0 | 0.0% | Q1 2025 | Oct 08, 2025 |
| TWO SIGMA ADVISERS, LP | History | Reduced | 15,100 | 37 | 0.0% | 0.0% | 52 | -1,600 | -9.58% | Q1 2025 | May 15, 2025 |
| BANK OF MONTREAL /CAN/ | History | Added to | 15,227 | 37 | 0.0% | 0.0% | 51 | +695 | 4.78% | Q1 2025 | May 13, 2025 |
| Police & Firemen's Retirement System of New Jersey | History | No change | 14,886 | 36 | 0.0% | 0.0% | 53 | 0 | 0.0% | Q1 2025 | May 09, 2025 |
| SEI INVESTMENTS CO | History | No change | 10,782 | 26 | 0.0% | 0.0% | 54 | 0 | 0.0% | Q1 2025 | May 14, 2025 |
| Cerity Partners LLC | History | New | 10,419 | 25 | 0.0% | — | 55 | +10,419 | New | Q1 2025 | Apr 30, 2025 |
| Quadrature Capital Ltd | History | New | 10,246 | 25 | 0.0% | — | 56 | +10,246 | New | Q1 2025 | May 13, 2025 |
| HighTower Advisors, LLC | History | Reduced | 10,031 | 24 | 0.0% | 0.0% | 57 | -155 | -1.52% | Q1 2025 | May 13, 2025 |
| GROUP ONE TRADING LLC | History | Added to | 7,662 | 18 | 0.0% | 0.0% | 58 | +5,117 | 201.06% | Q1 2025 | May 14, 2025 |
| Legal & General Group Plc | History | No change | 6,625 | 16 | 0.0% | 0.0% | 59 | 0 | 0.0% | Q1 2025 | May 15, 2025 |
| ROYAL BANK OF CANADA | History | Reduced | 5,263 | 13 | 0.0% | 0.0% | 60 | -17,265 | -76.64% | Q1 2025 | Nov 21, 2025 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | History | No change | 5,289 | 13 | 0.0% | 0.0% | 61 | 0 | 0.0% | Q1 2025 | May 15, 2025 |
| FMR LLC | History | Reduced | 4,976 | 12 | 0.0% | 0.0% | 62 | -159,335 | -96.97% | Q1 2025 | May 12, 2025 |
| BNP PARIBAS FINANCIAL MARKETS | History | Reduced | 5,061 | 12 | 0.0% | 0.0% | 63 | -70,053 | -93.26% | Q1 2025 | May 14, 2025 |
| Tower Research Capital LLC (TRC) | History | Reduced | 3,637 | 8 | 0.0% | 0.0% | 64 | -3,260 | -47.27% | Q1 2025 | May 15, 2025 |
| Mirae Asset Global Investments Co., Ltd. | History | Added to | 3,370 | 8 | 0.0% | 0.0% | 65 | +27 | 0.81% | Q1 2025 | Apr 24, 2025 |
| GF FUND MANAGEMENT CO. LTD. | History | Added to | 2,569 | 6 | 0.0% | 0.0% | 66 | +462 | 21.93% | Q1 2025 | Apr 29, 2025 |
| Sterling Capital Management LLC | History | Reduced | 1,311 | 3 | 0.0% | 0.0% | 67 | -1,028 | -43.95% | Q1 2025 | May 13, 2025 |
| Siren, L.L.C. | History | Closed out | 0 | 0 | — | 0.24% | — | -1,729,665 | -100.0% | Q4 2024 | Feb 14, 2025 |
| RTW INVESTMENTS, LP | History | Closed out | 0 | 0 | — | 0.05% | — | -978,310 | -100.0% | Q4 2024 | Feb 14, 2025 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | History | Closed out | 0 | 0 | — | 0.01% | — | -662,981 | -100.0% | Q4 2024 | Feb 14, 2025 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | History | Closed out | 0 | 0 | — | 0.0% | — | -450,000 | -100.0% | Q4 2024 | Feb 14, 2025 |
| KENNEDY CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.03% | — | -446,850 | -100.0% | Q4 2024 | Feb 13, 2025 |
| TD ASSET MANAGEMENT INC | History | Closed out | 0 | 0 | — | 0.0% | — | -267,656 | -100.0% | Q4 2024 | Feb 11, 2025 |
| AMERIPRISE FINANCIAL INC | History | Closed out | 0 | 0 | — | 0.0% | — | -228,098 | -100.0% | Q4 2024 | Feb 14, 2025 |
| Hudson Bay Capital Management LP | History | Closed out | 0 | 0 | — | 0.0% | — | -196,620 | -100.0% | Q4 2024 | Feb 14, 2025 |
| ExodusPoint Capital Management, LP | History | Closed out | 0 | 0 | — | 0.0% | — | -134,680 | -100.0% | Q4 2024 | Feb 12, 2025 |
| MARTINGALE ASSET MANAGEMENT L P | History | Closed out | 0 | 0 | — | 0.01% | — | -102,596 | -100.0% | Q4 2024 | Feb 13, 2025 |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | History | Closed out | 0 | 0 | — | 0.0% | — | -97,347 | -100.0% | Q4 2024 | Feb 19, 2025 |
| Russell Investments Group, Ltd. | History | Closed out | 0 | 0 | — | 0.0% | — | -66,699 | -100.0% | Q4 2024 | Feb 13, 2025 |
| TUDOR INVESTMENT CORP ET AL | History | Closed out | 0 | 0 | — | 0.0% | — | -48,299 | -100.0% | Q4 2024 | Feb 14, 2025 |
| BOOTHBAY FUND MANAGEMENT, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -29,828 | -100.0% | Q4 2024 | Feb 14, 2025 |
| Verition Fund Management LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -27,480 | -100.0% | Q4 2024 | Feb 14, 2025 |
| ProShare Advisors LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -25,307 | -100.0% | Q4 2024 | Feb 14, 2025 |
| Man Group plc | History | Closed out | 0 | 0 | — | 0.0% | — | -15,193 | -100.0% | Q4 2024 | Feb 14, 2025 |
| PRUDENTIAL FINANCIAL INC | History | Closed out | 0 | 0 | — | 0.0% | — | -14,130 | -100.0% | Q4 2024 | Feb 11, 2025 |
| HSBC HOLDINGS PLC | History | Closed out | 0 | 0 | — | 0.0% | — | -11,663 | -100.0% | Q4 2024 | Feb 14, 2025 |
| JANE STREET GROUP, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -10,031 | -100.0% | Q4 2024 | Feb 14, 2025 |
| SIMPLEX TRADING, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -4,899 | -100.0% | Q4 2024 | Feb 11, 2025 |
| FEDERATED HERMES, INC. | History | Closed out | 0 | 0 | — | 0.0% | — | -2,859 | -100.0% | Q4 2024 | Feb 13, 2025 |
| COMERICA BANK | History | Closed out | 0 | 0 | — | 0.0% | — | -1,428 | -100.0% | Q4 2024 | Feb 14, 2025 |
| SIGNATUREFD, LLC | History | Closed out | 0 | 0 | — | — | — | -175 | -100.0% | Q4 2024 | Feb 10, 2025 |
| Allworth Financial LP | History | Closed out | 0 | 0 | — | — | — | -65 | -100.0% | Q4 2024 | Jan 30, 2025 |
| PNC FINANCIAL SERVICES GROUP, INC. | History | Added to | 71 | 0 | — | — | — | +18 | 33.96% | Q1 2025 | May 09, 2025 |