Third Harmonic Bio, Inc. - 88427A107
Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 1 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DIMENSIONAL FUND ADVISORS LP | History | No change | 93,939 | 505 | 0.0% | 0.0% | 1 | 0 | 0.0% | Q3 2025 | Nov 12, 2025 |
| CANTOR FITZGERALD, L. P. | History | New | 86,325 | 464 | 0.0% | — | 2 | +86,325 | New | Q3 2025 | Feb 17, 2026 |
| RHUMBLINE ADVISERS | History | Reduced | 20,707 | 111 | 0.0% | 0.0% | 3 | -12,965 | -38.5% | Q3 2025 | Nov 06, 2025 |
| MetLife Investment Management, LLC | History | No change | 16,859 | 90 | 0.0% | 0.0% | 4 | 0 | 0.0% | Q3 2025 | Nov 13, 2025 |
| JBF Capital, Inc. | History | New | 250,000 | 7 | 0.0% | — | 5 | +250,000 | New | Q3 2025 | Nov 14, 2025 |
| Russell Investments Group, Ltd. | History | Added to | 803 | 4 | 0.0% | 0.0% | 7 | +534 | 198.51% | Q3 2025 | Nov 13, 2025 |
| AMALGAMATED BANK | History | No change | 665 | 4 | 0.0% | 0.0% | 6 | 0 | 0.0% | Q3 2025 | Oct 29, 2025 |
| GAMMA Investing LLC | History | Added to | 458 | 2 | 0.0% | — | 8 | +353 | 336.19% | Q3 2025 | Oct 02, 2025 |
| Optiver Holding B.V. | History | New | 196 | 1 | 0.0% | — | 9 | +196 | New | Q3 2025 | Nov 10, 2025 |
| Atlas Venture Life Science Advisors, LLC | History | Closed out | 0 | 0 | — | 8.53% | — | -10,402,286 | -100.0% | Q2 2025 | Aug 12, 2025 |
| ORBIMED ADVISORS LLC | History | Closed out | 0 | 0 | — | 0.78% | — | -5,779,071 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Nantahala Capital Management, LLC | History | Closed out | 0 | 0 | — | 0.63% | — | -2,938,700 | -100.0% | Q2 2025 | Aug 14, 2025 |
| TCG Crossover Management, LLC | History | Closed out | 0 | 0 | — | 1.19% | — | -1,915,424 | -100.0% | Q2 2025 | Aug 14, 2025 |
| BlackRock, Inc. | History | Closed out | 0 | 0 | — | 0.0% | — | -1,726,614 | -100.0% | Q2 2025 | Aug 12, 2025 |
| VANGUARD GROUP INC | History | Closed out | 0 | 0 | — | 0.0% | — | -1,298,089 | -100.0% | Q2 2025 | Aug 11, 2025 |
| D. E. Shaw & Co., Inc. | History | Closed out | 0 | 0 | — | 0.0% | — | -1,250,680 | -100.0% | Q2 2025 | Aug 14, 2025 |
| TANG CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.26% | — | -929,727 | -100.0% | Q2 2025 | Aug 14, 2025 |
| ADAR1 Capital Management, LLC | History | Closed out | 0 | 0 | — | 0.52% | — | -622,873 | -100.0% | Q2 2025 | Aug 14, 2025 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -577,190 | -100.0% | Q2 2025 | Aug 08, 2025 |
| DLD Asset Management, LP | History | Closed out | 0 | 0 | — | 0.23% | — | -503,841 | -100.0% | Q2 2025 | Aug 13, 2025 |
| STATE STREET CORP | History | Closed out | 0 | 0 | — | 0.0% | — | -468,994 | -100.0% | Q2 2025 | Aug 14, 2025 |
| OMERS ADMINISTRATION Corp | History | Closed out | 0 | 0 | — | 0.02% | — | -426,900 | -100.0% | Q2 2025 | Aug 13, 2025 |
| Affinity Asset Advisors, LLC | History | Closed out | 0 | 0 | — | 0.27% | — | -370,000 | -100.0% | Q2 2025 | Aug 13, 2025 |
| Alpine Global Management, LLC | History | Closed out | 0 | 0 | — | 0.41% | — | -334,481 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Yakira Capital Management, Inc. | History | Closed out | 0 | 0 | — | 0.54% | — | -293,633 | -100.0% | Q2 2025 | Aug 13, 2025 |
| Rangeley Capital, LLC | History | Closed out | 0 | 0 | — | 1.88% | — | -290,000 | -100.0% | Q2 2025 | Aug 14, 2025 |
| MORGAN STANLEY | History | Closed out | 0 | 0 | — | 0.0% | — | -272,473 | -100.0% | Q2 2025 | Aug 14, 2025 |
| GABELLI & Co INVESTMENT ADVISERS, INC. | History | Closed out | 0 | 0 | — | 0.21% | — | -251,681 | -100.0% | Q2 2025 | Aug 13, 2025 |
| Alberta Investment Management Corp | History | Closed out | 0 | 0 | — | 0.01% | — | -239,389 | -100.0% | Q2 2025 | Feb 17, 2026 |
| Vazirani Asset Management LLC | History | Closed out | 0 | 0 | — | 4.68% | — | -225,500 | -100.0% | Q2 2025 | Aug 14, 2025 |
| GOLDMAN SACHS GROUP INC | History | Closed out | 0 | 0 | — | 0.0% | — | -221,090 | -100.0% | Q2 2025 | Aug 14, 2025 |
| 683 Capital Management, LLC | History | Closed out | 0 | 0 | — | 0.07% | — | -200,000 | -100.0% | Q2 2025 | Aug 14, 2025 |
| LMR Partners LLP | History | Closed out | 0 | 0 | — | 0.01% | — | -200,000 | -100.0% | Q2 2025 | Aug 14, 2025 |
| NORTHERN TRUST CORP | History | Closed out | 0 | 0 | — | 0.0% | — | -197,549 | -100.0% | Q2 2025 | Aug 13, 2025 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | Closed out | 0 | 0 | — | 0.0% | — | -185,797 | -100.0% | Q2 2025 | Aug 12, 2025 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | Closed out | 0 | 0 | — | 0.0% | — | -160,683 | -100.0% | Q2 2025 | Aug 14, 2025 |
| CITADEL ADVISORS LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -148,670 | -100.0% | Q2 2025 | Aug 14, 2025 |
| FNY Investment Advisers, LLC | History | Closed out | 0 | 0 | — | 0.23% | — | -100,100 | -100.0% | Q2 2025 | Jul 30, 2025 |
| Qube Research & Technologies Ltd | History | Closed out | 0 | 0 | — | 0.0% | — | -97,024 | -100.0% | Q2 2025 | Aug 14, 2025 |
| JPMORGAN CHASE & CO | History | Closed out | 0 | 0 | — | 0.0% | — | -95,538 | -100.0% | Q2 2025 | Aug 12, 2025 |
| PRELUDE CAPITAL MANAGEMENT, LLC | History | Closed out | 0 | 0 | — | 0.04% | — | -76,822 | -100.0% | Q2 2025 | Aug 14, 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | History | Closed out | 0 | 0 | — | 0.0% | — | -75,658 | -100.0% | Q2 2025 | Aug 14, 2025 |
| AQR CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -73,646 | -100.0% | Q2 2025 | Aug 14, 2025 |
| BNP PARIBAS FINANCIAL MARKETS | History | Closed out | 0 | 0 | — | 0.0% | — | -73,526 | -100.0% | Q2 2025 | Aug 14, 2025 |
| MILLENNIUM MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -59,360 | -100.0% | Q2 2025 | Aug 14, 2025 |
| TWO SIGMA INVESTMENTS, LP | History | Closed out | 0 | 0 | — | 0.0% | — | -58,829 | -100.0% | Q2 2025 | Aug 14, 2025 |
| BARCLAYS PLC | History | Closed out | 0 | 0 | — | 0.0% | — | -56,905 | -100.0% | Q2 2025 | Feb 27, 2026 |
| Bank of New York Mellon Corp | History | Closed out | 0 | 0 | — | 0.0% | — | -53,358 | -100.0% | Q2 2025 | Aug 05, 2025 |
| UBS Group AG | History | Closed out | 0 | 0 | — | 0.0% | — | -52,256 | -100.0% | Q2 2025 | Aug 14, 2025 |
| MARTINGALE ASSET MANAGEMENT L P | History | Closed out | 0 | 0 | — | 0.01% | — | -51,113 | -100.0% | Q2 2025 | Aug 11, 2025 |
| Squarepoint Ops LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -51,099 | -100.0% | Q2 2025 | Aug 27, 2025 |
| FIFTH LANE CAPITAL, LP | History | Closed out | 0 | 0 | — | 0.33% | — | -50,000 | -100.0% | Q2 2025 | Aug 13, 2025 |
| STRS OHIO | History | Closed out | 0 | 0 | — | 0.0% | — | -42,400 | -100.0% | Q2 2025 | Aug 04, 2025 |
| AMERICAN CENTURY COMPANIES INC | History | Closed out | 0 | 0 | — | 0.0% | — | -34,299 | -100.0% | Q2 2025 | Aug 12, 2025 |
| BANK OF AMERICA CORP /DE/ | History | Closed out | 0 | 0 | — | 0.0% | — | -34,230 | -100.0% | Q2 2025 | Aug 14, 2025 |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -31,785 | -100.0% | Q2 2025 | Aug 14, 2025 |
| PDT Partners, LLC | History | Closed out | 0 | 0 | — | 0.01% | — | -30,118 | -100.0% | Q2 2025 | Aug 14, 2025 |
| HSBC HOLDINGS PLC | History | Closed out | 0 | 0 | — | 0.0% | — | -27,758 | -100.0% | Q2 2025 | Aug 13, 2025 |
| OCCUDO QUANTITATIVE STRATEGIES LP | History | Closed out | 0 | 0 | — | 0.02% | — | -26,994 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Walleye Capital LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -24,275 | -100.0% | Q2 2025 | Aug 13, 2025 |
| ALLIANCEBERNSTEIN L.P. | History | Closed out | 0 | 0 | — | 0.0% | — | -20,830 | -100.0% | Q2 2025 | Aug 14, 2025 |
| PERISCOPE CAPITAL INC. | History | Closed out | 0 | 0 | — | 0.02% | — | -20,000 | -100.0% | Q2 2025 | Aug 14, 2025 |
| DEUTSCHE BANK AG\ | History | Closed out | 0 | 0 | — | 0.0% | — | -19,815 | -100.0% | Q2 2025 | Aug 12, 2025 |
| JANE STREET GROUP, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -18,900 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Graham Capital Management, L.P. | History | Closed out | 0 | 0 | — | 0.0% | — | -17,112 | -100.0% | Q2 2025 | Aug 14, 2025 |
| CSS LLC/IL | History | Closed out | 0 | 0 | — | 0.0% | — | -17,000 | -100.0% | Q2 2025 | Aug 14, 2025 |
| WELLS FARGO & COMPANY/MN | History | Closed out | 0 | 0 | — | 0.0% | — | -16,118 | -100.0% | Q2 2025 | Aug 14, 2025 |
| ROYAL BANK OF CANADA | History | Closed out | 0 | 0 | — | 0.0% | — | -15,699 | -100.0% | Q2 2025 | Nov 21, 2025 |
| INTECH INVESTMENT MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -15,578 | -100.0% | Q2 2025 | Aug 08, 2025 |
| FARALLON CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.06% | — | -15,361 | -100.0% | Q2 2025 | Feb 17, 2026 |
| XTX Topco Ltd | History | Closed out | 0 | 0 | — | 0.0% | — | -14,703 | -100.0% | Q2 2025 | Aug 12, 2025 |
| CITIGROUP INC | History | Closed out | 0 | 0 | — | 0.0% | — | -14,220 | -100.0% | Q2 2025 | Aug 11, 2025 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | History | Closed out | 0 | 0 | — | 0.0% | — | -13,214 | -100.0% | Q2 2025 | Aug 14, 2025 |
| AlphaQuest LLC | History | Closed out | 0 | 0 | — | 0.01% | — | -11,873 | -100.0% | Q2 2025 | Jul 31, 2025 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | Closed out | 0 | 0 | — | 0.0% | — | -11,811 | -100.0% | Q2 2025 | Aug 14, 2025 |
| China Universal Asset Management Co., Ltd. | History | Closed out | 0 | 0 | — | 0.0% | — | -9,064 | -100.0% | Q2 2025 | Aug 28, 2025 |
| NEW YORK STATE COMMON RETIREMENT FUND | History | Closed out | 0 | 0 | — | 0.0% | — | -5,976 | -100.0% | Q2 2025 | Oct 08, 2025 |
| CWM, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -4,897 | -100.0% | Q2 2025 | Jul 25, 2025 |
| FMR LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -4,406 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Police & Firemen's Retirement System of New Jersey | History | Closed out | 0 | 0 | — | 0.0% | — | -3,986 | -100.0% | Q2 2025 | Aug 08, 2025 |
| Tower Research Capital LLC (TRC) | History | Closed out | 0 | 0 | — | 0.0% | — | -3,907 | -100.0% | Q2 2025 | Aug 15, 2025 |
| Legal & General Group Plc | History | Closed out | 0 | 0 | — | 0.0% | — | -2,323 | -100.0% | Q2 2025 | Aug 12, 2025 |
| Mirae Asset Global Investments Co., Ltd. | History | Closed out | 0 | 0 | — | 0.0% | — | -1,743 | -100.0% | Q2 2025 | Jul 21, 2025 |
| Versant Capital Management, Inc | History | Closed out | 0 | 0 | — | 0.0% | — | -1,595 | -100.0% | Q2 2025 | Jul 07, 2025 |
| ATWOOD & PALMER INC | History | Closed out | 0 | 0 | — | 0.0% | — | -1,500 | -100.0% | Q2 2025 | Jul 08, 2025 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | History | Closed out | 0 | 0 | — | 0.0% | — | -1,437 | -100.0% | Q2 2025 | Aug 14, 2025 |
| PNC FINANCIAL SERVICES GROUP, INC. | History | Closed out | 0 | 0 | — | 0.0% | — | -1,325 | -100.0% | Q2 2025 | Aug 08, 2025 |
| GF FUND MANAGEMENT CO. LTD. | History | Closed out | 0 | 0 | — | 0.0% | — | -1,118 | -100.0% | Q2 2025 | Jul 22, 2025 |
| CALDWELL SUTTER CAPITAL, INC. | History | New | 1,000 | 0 | — | — | — | +1,000 | New | Q3 2025 | Oct 29, 2025 |
| Sterling Capital Management LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -625 | -100.0% | Q2 2025 | Aug 08, 2025 |
| ROTHSCHILD INVESTMENT LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -255 | -100.0% | Q2 2025 | Aug 11, 2025 |
| True Wealth Design, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -211 | -100.0% | Q2 2025 | Aug 06, 2025 |
| Physician Wealth Advisors, Inc. | History | Closed out | 0 | 0 | — | 0.0% | — | -195 | -100.0% | Q2 2025 | Jul 14, 2025 |
| Daiwa Securities Group Inc. | History | Closed out | 0 | 0 | — | 0.0% | — | -149 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Rise Advisors, LLC | History | Closed out | 0 | 0 | — | — | — | -144 | -100.0% | Q2 2025 | Jul 08, 2025 |
| GROUP ONE TRADING LLC | History | Closed out | 0 | 0 | — | — | — | -100 | -100.0% | Q2 2025 | Aug 14, 2025 |
| Fortitude Family Office, LLC | History | Closed out | 0 | 0 | — | — | — | -97 | -100.0% | Q2 2025 | Jul 15, 2025 |
| OSAIC HOLDINGS, INC. | History | New | 69 | 0 | — | — | — | +69 | New | Q3 2025 | Nov 14, 2025 |
| EverSource Wealth Advisors, LLC | History | Closed out | 0 | 0 | — | — | — | -50 | -100.0% | Q2 2025 | Aug 13, 2025 |
| Capital Advisors, Ltd. LLC | History | Closed out | 0 | 0 | — | — | — | -9 | -100.0% | Q2 2025 | Jul 24, 2025 |
| IFP Advisors, Inc | History | New | 1 | 0 | — | 0.0% | — | +1 | New | Q3 2025 | Feb 06, 2026 |
| MEEDER ASSET MANAGEMENT INC | History | No change | 2,083 | 0 | — | 0.0% | — | 0 | 0.0% | Q3 2025 | Oct 24, 2025 |
| NISA INVESTMENT ADVISORS, LLC | History | No change | 3,423 | 0 | — | 0.0% | — | 0 | 0.0% | Q3 2025 | Oct 23, 2025 |
| Ameritas Investment Partners, Inc. | History | No change | 2,017 | 0 | — | 0.0% | — | 0 | 0.0% | Q3 2025 | Nov 10, 2025 |
| BML Capital Management, LLC | History | No change | 3,824,417 | 0 | — | 15.71% | — | 0 | 0.0% | Q3 2025 | Nov 10, 2025 |
| SBI Securities Co., Ltd. | History | No change | 20 | 0 | — | — | — | 0 | 0.0% | Q3 2025 | Nov 05, 2025 |
| Nuveen, LLC | History | No change | 27,963 | 0 | — | 0.0% | — | 0 | 0.0% | Q3 2025 | Nov 12, 2025 |