Propel Bio Management, LLC

Q4 2025 13F-HR Holdings

Location
Los Angeles, CA
Holdings as of
12/31/2025
Date filed
2/11/2026
Form type
13F-HR
Num holdings
20
Total value ($000)
$117,124
Net value change ($000)
+17,229 (17.2%)
New positions
8
Sold out positions
4
Turnover %
37.6%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 11/12/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ACHV 6,892 57.8%
VRDN 6,850 352.7%
KYTX 6,267 NEW
PHAT 5,784 88.9%
IVA 4,650 NEW
OCS 3,452 NEW
CMPS 3,024 103.5%
SABS 2,442 NEW
RGNX 1,683 NEW
PAGP 1,145 4.9%
Top Reduces (Value $000, Stocks/ETFs)
AKRO -10,867 -100.0%
APLT -6,827 -100.0%
TCRX -3,517 -100.0%
JSPR -2,449 -100.0%
MIST -1,931 -18.8%
ZVRA -1,634 -74.1%
ABEO -765 -14.9%
DCTH -285 -6.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type