BAKER BROS. ADVISORS LP
Q4 2021 13F-HR Holdings
Net value change ($000)
-2,218,042
(-9.7%)
New positions
5
Sold out positions
5
Turnover %
0.8%
Sector allocation + QoQ delta (equities-only)
Snapshot: Change Analysis
Compared to Q3 2021
Methodology:
sector metrics are equities-only;
instrument mix chart is ex-options;
options exposure is shown separately.
Why this matters.
Top Adds (Value $000, Stocks/ETFs)
| ACAD | 282,059 | 40.5% |
| INCY | 265,084 | 12.0% |
| BMRN | 84,283 | 14.3% |
| TRDA | 80,540 | NEW |
| ChemoCentryx, Inc. | 54,244 | 1053.3% |
| ARGX | 53,952 | 16.0% |
| TVTX | 33,383 | 67.5% |
| KRYS | 24,771 | 78.1% |
| 2seventy bio, Inc. | 21,356 | NEW |
| Merus N.V. | 19,968 | 44.5% |
Top Reduces (Value $000, Stocks/ETFs)
| ONC | -1,074,356 | -25.4% |
| Seagen Inc. | -779,832 | -9.7% |
| PRLD | -190,328 | -60.2% |
| KOD | -164,431 | -11.7% |
| Invitae Corp | -129,935 | -46.3% |
| IGM Biosciences, Inc. | -114,977 | -55.4% |
| ASND | -112,904 | -15.6% |
| Allakos Inc. | -67,549 | -90.8% |
| ABCL | -59,984 | -28.6% |
| DBVT | -48,227 | -67.3% |
Instrument mix + QoQ Δ (ex-options)
How this table is calculated:
SEC
VALUE ($000) is used as reported.
For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received.
Column % is bucket-based:
non-options share is calculated inside non-option total, options share is calculated inside options total.
Details.
Filter:
Instrument:
| Issuer Name | Ticker | Sector | Industry | Class | History | Value ($000) | % | Shares | Shares Δ | Shares Δ% | Value Δ ($000) | Value Δ% | Principal | Option Type |
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