BAKER BROS. ADVISORS LP

Q3 2021 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2021
Date filed
11/15/2021
Form type
13F-HR
Num holdings
122
Total value ($000)
$22,771,634
Net value change ($000)
+1,736 (0.0%)
New positions
11
Sold out positions
10
Turnover %
1.4%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Seagen Inc. 563,676 7.6%
ASND 258,163 55.4%
ONC 231,161 5.8%
KOD 94,289 7.2%
LEGN 51,195 74.9%
TVTX 46,737 1713.9%
KYMR 45,058 47.4%
bluebird bio, Inc. 40,511 558.1%
PACB 27,146 24.2%
PRLD 26,525 9.2%
Top Reduces (Value $000, Stocks/ETFs)
INCY -491,506 -18.2%
ACAD -326,065 -31.9%
APLS -143,585 -100.0%
Invitae Corp -64,981 -18.8%
IGM Biosciences, Inc. -55,043 -21.0%
BMRN -44,263 -7.0%
HRTX -39,276 -31.1%
TLIS -36,207 -43.3%
ADCT -34,531 -100.0%
Global Blood Therapeutics, Inc. -30,695 -27.2%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type