BAKER BROS. ADVISORS LP

Q3 2024 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2024
Date filed
11/14/2024
Form type
13F-HR
Num holdings
93
Total value ($000)
$9,648,758
Net value change ($000)
+1,823,680 (23.3%)
New positions
6
Sold out positions
7
Turnover %
1.0%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2024 Next filing: 2/14/2025 SEC filing

Snapshot: Change Analysis

Compared to Q2 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ONC 864,958 57.4%
SMMT 353,772 195.3%
INCY 168,480 9.0%
KYMR 104,809 58.6%
INSM 82,767 34.5%
RYTM 72,493 27.6%
EWTX 50,692 48.2%
RVMD 49,502 16.9%
IGM Biosciences, Inc. 39,587 140.9%
CRSP 34,207 633.3%
Top Reduces (Value $000, Stocks/ETFs)
MDGL -134,154 -24.3%
ACAD -37,304 -5.4%
Cerevel Therapeutics Holdings, Inc. -27,952 -100.0%
PRLD -17,616 -45.7%
ABCL -9,909 -12.2%
LONA -8,358 -100.0%
STOK -5,330 -9.0%
TLIS -4,403 -100.0%
IMCR -4,182 -8.1%
ALMS -4,093 -19.7%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type