Foresite Capital Management VI LLC

Q4 2025 13F-HR Holdings

Location
West Hollywood, CA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
12
Total value ($000)
$330,839
Net value change ($000)
+71,972 (27.8%)
New positions
3
Sold out positions
3
Turnover %
17.0%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ALMS 24,509 144.6%
NTRA 15,431 NEW
AGIO 14,427 NEW
RAPT 12,625 31.3%
ATAI 11,248 NEW
KYMR 3,104 37.5%
CGON 2,755 3.1%
CNTA 2,249 7.1%
DNLI 1,990 13.7%
VSTM 1,111 4.8%
Top Reduces (Value $000, Stocks/ETFs)
AKRO -11,628 -100.0%
CRVS -2,124 -16.6%
RNAM -1,743 -100.0%
CASI -1,627 -100.0%
HNGE -355 -5.4%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type