Foresite Capital Management VI LLC

Q3 2025 13F-HR Holdings

Location
Larkspur, CA
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
12
Total value ($000)
$258,867
Net value change ($000)
+80,983 (45.5%)
New positions
1
Sold out positions
9
Turnover %
20.2%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/12/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
CGON 31,723 54.9%
RAPT 27,797 222.4%
VSTM 17,794 335.9%
CNTA 15,396 93.5%
DNLI 14,520 NEW
CRVS 5,834 84.2%
ALMS 4,205 33.0%
KYMR 1,896 29.7%
CASI 698 75.1%
RNAM 607 53.4%
Top Reduces (Value $000, Stocks/ETFs)
BCAX -8,819 -100.0%
EWTX -7,669 -100.0%
XENE -5,008 -100.0%
CGEM -4,473 -100.0%
GPCR -4,355 -100.0%
ALLO -3,249 -100.0%
IDYA -3,037 -100.0%
AKRO -1,440 -11.0%
SYRE -1,048 -100.0%
HNGE -360 -5.2%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type