Sofinnova Investments, Inc.

Q2 2026 13F-HR Holdings

Location
Menlo Park, CA
Holdings as of
6/30/2026
Date filed
8/14/2026
Form type
13F-HR
Num holdings
57
Total value ($000)
$1,934,262
Net value change ($000)
-696,892 (-26.5%)
New positions
11
Sold out positions
19
Turnover %
27.1%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NTRA 110,784 35.7%
GMAB 90,939 450.6%
Seaport Therapeutics Inc 77,429 NEW
GILD 43,347 NEW
AVBP 19,801 50.6%
RAPP 19,768 33.2%
ANAB 19,546 142.0%
BIOA 16,103 40.1%
MANE 13,687 295.6%
NRIX 12,715 NEW
Top Reduces (Value $000, Stocks/ETFs)
AZN -89,938 -100.0%
BMY -70,085 -58.1%
UTHR -53,474 -56.3%
BIIB -42,078 -100.0%
CELC -41,795 -100.0%
COGT -41,291 -50.8%
INSM -39,702 -70.2%
ALC -37,837 -68.8%
BBIO -30,386 -100.0%
JAZZ -25,078 -22.2%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 62,235 (3.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type