ORBIMED ADVISORS LLC

Q4 2020 13F-HR Holdings

Location
New York, NY
Holdings as of
12/31/2020
Date filed
2/16/2021
Form type
13F-HR
Num holdings
149
Total value ($000)
$11,428,040
Net value change ($000)
+3,471,857 (43.6%)
New positions
26
Sold out positions
19
Turnover %
16.4%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q3 2020
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PRLD 645,939 137.5%
SPRY 405,053 NEW
ABCL 338,047 NEW
PMVP 190,664 73.3%
SpringWorks Therapeutics, Inc. 184,046 52.1%
Prevail Therapeutics Inc. 178,171 126.6%
Kinnate Biopharma Inc. 153,071 NEW
UNH 136,870 NEW
PFE 133,127 NEW
ELV 99,698 NEW
Top Reduces (Value $000, Stocks/ETFs)
ALXN -223,567 -89.4%
BIIB -73,458 -36.2%
XLRN -67,638 -100.0%
EXEL -58,780 -100.0%
ASND -57,227 -50.5%
ELDN -54,435 -100.0%
NVO -22,912 -100.0%
BNR -22,897 -19.2%
Tricida, Inc. -19,324 -22.2%
IVERIC bio, Inc. -19,243 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 9,754 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type