ORBIMED ADVISORS LLC

Q1 2021 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2021
Date filed
5/17/2021
Form type
13F-HR
Num holdings
158
Total value ($000)
$10,694,926
Net value change ($000)
-733,114 (-6.4%)
New positions
32
Sold out positions
27
Turnover %
24.7%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q4 2020
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
EWTX 453,202 NEW
Gracell Biotechnologies Inc. 121,427 NEW
HAE 94,581 NEW
XTNT 84,901 97.5%
TERN 83,406 NEW
IMA 82,884 NEW
GH 79,837 115.1%
IRON 78,945 NEW
CMMB 74,019 NEW
MRK 70,200 32.3%
Top Reduces (Value $000, Stocks/ETFs)
PRLD -680,793 -61.0%
Prevail Therapeutics Inc. -318,884 -100.0%
PMVP -209,796 -46.5%
PFE -133,127 -100.0%
CNC -119,682 -100.0%
Turning Point Therapeutics, Inc. -111,160 -33.2%
CALC -106,782 -82.2%
BIIB -106,689 -82.3%
IOVA -97,949 -31.8%
AGIO -95,643 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 29,567 (0.3% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type