ORBIMED ADVISORS LLC

Q1 2021 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2021
Date filed
5/17/2021
Form type
13F-HR
Num holdings
159
Total value ($000)
$10,694,926
Net value change ($000)
-733,114 (-6.4%)
New positions
32
Sold out positions
27
Turnover %
24.7%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2020
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
EWTX 453,202 NEW
Gracell Biotechnologies Inc. 121,427 NEW
HAE 94,581 NEW
XTNT 84,901 97.5%
TERN 83,406 NEW
IMA 82,884 NEW
GH 79,837 115.1%
IRON 78,945 NEW
CMMB 74,019 NEW
MRK 70,200 32.3%
Top Reduces (Value $000, Stocks/ETFs)
PRLD -680,793 -61.0%
Prevail Therapeutics Inc. -318,884 -100.0%
PMVP -209,796 -46.5%
PFE -133,127 -100.0%
CNC -119,682 -100.0%
Turning Point Therapeutics, Inc. -111,160 -33.2%
CALC -106,782 -82.2%
BIIB -106,689 -82.3%
IOVA -97,949 -31.8%
AGIO -95,643 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 29,567 (0.3% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 ORBIMED CAPITAL LLC 028-10410