ORBIMED ADVISORS LLC

Q1 2023 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2023
Date filed
5/15/2023
Form type
13F-HR
Num holdings
124
Total value ($000)
$5,094,046
Net value change ($000)
-133,412 (-2.6%)
New positions
18
Sold out positions
16
Turnover %
17.8%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q4 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ELVN 197,017 NEW
BIIB 68,904 96.4%
Theseus Pharmaceuticals, Inc. 67,211 78.3%
LLY 63,876 NEW
BAX 63,355 NEW
APLS 60,037 NEW
R1 RCM Inc. /DE 26,250 NEW
AMLX 23,868 NEW
REGN 19,720 NEW
AMGN 18,542 NEW
Top Reduces (Value $000, Stocks/ETFs)
Seagen Inc. -117,434 -100.0%
PFE -71,408 -100.0%
UNH -71,298 -35.3%
89bio, Inc. -46,577 -100.0%
ACRS -43,445 -100.0%
CMPX -39,358 -35.0%
PCVX -34,187 -55.6%
VRNA -33,919 -28.4%
EWTX -33,068 -25.4%
NBIX -32,642 -39.7%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 44,859 (0.9% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type