ORBIMED ADVISORS LLC

Q1 2023 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2023
Date filed
5/15/2023
Form type
13F-HR
Num holdings
125
Total value ($000)
$5,094,046
Net value change ($000)
-133,412 (-2.6%)
New positions
18
Sold out positions
16
Turnover %
17.8%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ELVN 197,017 NEW
BIIB 68,904 96.4%
Theseus Pharmaceuticals, Inc. 67,211 78.3%
LLY 63,876 NEW
BAX 63,355 NEW
APLS 60,037 NEW
R1 RCM Inc. /DE 26,250 NEW
AMLX 23,868 NEW
REGN 19,720 NEW
AMGN 18,542 NEW
Top Reduces (Value $000, Stocks/ETFs)
Seagen Inc. -117,434 -100.0%
PFE -71,408 -100.0%
UNH -71,298 -35.3%
89bio, Inc. -46,577 -100.0%
ACRS -43,445 -100.0%
CMPX -39,358 -35.0%
PCVX -34,187 -55.6%
VRNA -33,919 -28.4%
EWTX -33,068 -25.4%
NBIX -32,642 -39.7%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 44,859 (0.9% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 ORBIMED CAPITAL LLC 028-10410