ORBIMED ADVISORS LLC

Q1 2024 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2024
Date filed
5/15/2024
Form type
13F-HR
Num holdings
114
Total value ($000)
$5,459,960
Net value change ($000)
+452,716 (9.0%)
New positions
20
Sold out positions
17
Turnover %
18.0%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q4 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
JANX 125,374 352.2%
EWTX 114,631 71.9%
LLY 67,689 31.8%
MRK 58,630 51.0%
ALPINE IMMUNE SCIENCES, INC. 57,933 119.9%
AVBP 54,068 NEW
CYTK 47,864 NEW
SPRY 43,802 86.5%
GERN 41,526 4059.2%
QTTB 38,391 NEW
Top Reduces (Value $000, Stocks/ETFs)
RayzeBio, Inc. -147,045 -100.0%
Gracell Biotechnologies Inc. -93,460 -100.0%
UTHR -84,900 -100.0%
Theseus Pharmaceuticals, Inc. -71,740 -100.0%
R1 RCM Inc. /DE -50,770 -100.0%
HUM -50,313 -100.0%
BMRN -39,851 -26.3%
IOVA -38,272 -100.0%
SpringWorks Therapeutics, Inc. -33,472 -28.5%
Fusion Pharmaceuticals Inc. -30,010 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 12,910 (0.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type