ORBIMED ADVISORS LLC

Q1 2024 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2024
Date filed
5/15/2024
Form type
13F-HR
Num holdings
115
Total value ($000)
$5,459,960
Net value change ($000)
+452,716 (9.0%)
New positions
20
Sold out positions
17
Turnover %
18.0%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
JANX 125,374 352.2%
EWTX 114,631 71.9%
LLY 67,689 31.8%
MRK 58,630 51.0%
ALPINE IMMUNE SCIENCES, INC. 57,933 119.9%
AVBP 54,068 NEW
CYTK 47,864 NEW
SPRY 43,802 86.5%
GERN 41,526 4059.2%
QTTB 38,391 NEW
Top Reduces (Value $000, Stocks/ETFs)
RayzeBio, Inc. -147,045 -100.0%
Gracell Biotechnologies Inc. -93,460 -100.0%
UTHR -84,900 -100.0%
Theseus Pharmaceuticals, Inc. -71,740 -100.0%
R1 RCM Inc. /DE -50,770 -100.0%
HUM -50,313 -100.0%
BMRN -39,851 -26.3%
IOVA -38,272 -100.0%
SpringWorks Therapeutics, Inc. -33,472 -28.5%
Fusion Pharmaceuticals Inc. -30,010 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 12,910 (0.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 ORBIMED CAPITAL LLC 028-10410