Rock Springs Capital Management LP

Q3 2025 13F-HR Holdings

Location
Baltimore, MD
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
93
Total value ($000)
$1,711,524
Net value change ($000)
+106,735 (6.7%)
New positions
9
Sold out positions
10
Turnover %
5.8%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
TVTX 23,497 83.2%
MDGL 20,720 48.8%
RYTM 18,004 33.1%
CDTX 17,349 265.5%
MIRM 14,159 34.0%
RVMD 13,391 27.3%
MLYS 11,092 252.6%
COGT 8,734 152.0%
LENZ 8,541 346.9%
HTFL 8,415 NEW
Top Reduces (Value $000, Stocks/ETFs)
BPMC -23,777 -100.0%
UNH -15,754 -100.0%
OSCR -15,008 -100.0%
RARE -13,089 -25.9%
ACHC -11,583 -73.3%
LLY -10,395 -11.4%
WST -8,607 -77.1%
AGL -7,891 -52.4%
ISRG -7,887 -17.7%
NUVL -7,121 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 899 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type