Logos Global Management LP

Q4 2025 13F-HR Holdings

Location
San Francisco, CA
Holdings as of
12/31/2025
Date filed
2/17/2026
Form type
13F-HR
Num holdings
69
Total value ($000)
$1,654,958
Net value change ($000)
+539,272 (48.3%)
New positions
22
Sold out positions
11
Turnover %
26.9%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2025 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q3 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
PRAX 103,903 1568.3%
RVMD 77,575 94.9%
OLMA 48,807 155.4%
IDYA 46,808 76.5%
CDTX 32,566 90.7%
IMVT 30,520 688.5%
TERN 30,300 NEW
TNGX 29,232 366.3%
MLTX 23,065 NEW
ACAD 22,704 NEW
Top Reduces (Value $000, Stocks/ETFs)
AKRO -56,976 -100.0%
ARVN -47,499 -100.0%
VSTM -22,638 -63.3%
PTGX -19,929 -100.0%
KROS -13,447 -100.0%
JANX -9,051 -39.6%
AMLX -8,230 -41.8%
CNTA -7,729 -60.7%
COGT -7,180 -100.0%
IMRX -6,650 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 154,274 (9.3% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type